ABSTRACT
ABSTRACT Extranodal natural killer (NK)/T-cell lymphoma, nasal type, is a rare entity in otorhinolaryngology. Its management requires skilled physicians in order to suspect this disease and making a proper diagnosis at early stages. This paper reports the case of a 31-year-old male patient, with one month of nasal obstruction, recurrent sinusitis, palatal ulceration and a necrotizing lesion. Histopathology reported lymphoid infiltrate polymorph angiocentric growth pattern and extensive areas of necrosis. Immunohistochemistry confirmed the phenotype for T/NK cells: positive CD3, BCL2, CD4 and CD56. IgG for Epstein-Barr virus was also positive. The initial staging was T4, N1, M0, Eastern Cooperative Oncology Group (ECOG) scale was 1, with intermediate risk, and low International Prognostic Index (IPI); based on this results, the patient was referred to oncology to initiate treatment. After a ten-month follow-up, the patient's condition improved, with complete remission of nasal and palate injuries; no relapse has occurred to date. This case is a clear example of the importance of early diagnostic through multiple biopsies in order to establish a specific treatment to decrease complication rates and improve prognosis.
Subject(s)
Humans , Lymphoma, Extranodal NK-T-Cell , Radiotherapy , Granuloma, Lethal Midline , Antineoplastic ProtocolsABSTRACT
Objetivos: Disminuir los episodios de enfermedad respiratoria aguda (ERA) en las familias, mediante un enfoque modificado del modelo ecológico de Morelatto para identificar y trabajar colectivamente determinantes que influyen en la salud respiratoria de niños y niñas. Materiales y Métodos: Durante el proceso se realizaron actividades encaminadas a prevenir las principales causas de ERA basadas en el modelo transteórico del comportamiento con el fin de generar cambios conductuales en las familias. Para ello se creó una escala de valoración del riesgo de ERA como instrumento de medición de la efectividad de las actividades realizadas, otorgándole a cada familia un puntaje antes y después de la intervención para determinar si hubo disminución del mismo. Resultados: Las actividades realizadas conducen a cambios evidenciados en las prácticas cotidianos de las madres y sus familias, reflejadas en la escala de valoración de riesgos a partir de la disminución de conductas que favorecen la enfermedad respiratoria aguda y sus complicaciones en la primera infancia afiliada a la FAR -Génesis. Conclusiones: Una menor exposición a eventos y complicaciones de la ERA en miembros de grupos familiares de la FAR -Génesis puede contribuir a mejorar la resiliencia y disminuir la vulnerabilidad socioeconómica de las familias afectadas regularmente por la ERA sus complicaciones.
Objectives: To reduce acute respiratory disease (ARD) in children under six years of age. An ecological model approach modified by Morelatto guided community actions to identify and improve respiratory health determinants. Materials and Methods: During this process activities were implemented to change behaviors at the family level, regarding respiratory health practices according to the trans theoretical model of behavior. A risk scoring scale was used as a tool to track change in respiratory health related practices. Results: Project activities lead to behavioral changes in daily practices related ot ARD in mothers and their families, traced through the risk scoring scale. This approach allowed a participatory intervention of determinants related to ARD at different levels to improve respiratory health of children under six years of age. Conclusions: Fewer episodes and complications of respiratory disease among households may improve resilience and reduce socioeconomic vulnerability of families previously exposed to frequent events and complications of acute respiratory disease.